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Biology & Biological Sciences

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What is Biology & Biological Sciences?

Biology is the fascinating and ever-expanding field dedicated to studying life on Earth. It encompasses all living organisms, from the microscopic world of bacteria to the towering giants of the redwood forest. Biologists delve into the structure, function, growth, origin, evolution, and distribution of life across the planet.

What are the main topics involved with Biology & Biological Sciences?

  • Biochemistry: Focuses on the chemistry of life, exploring the structure, function, and interactions of molecules essential for biological processes.
  • Cell Biology: Examines the fundamental unit of life, the cell, its structure, function, and how different cell types work together in an organism.
  • Genetics: Investigates genes, heredity, and how traits are passed down from generation to generation.
  • Microbiology: Studies microscopic organisms like bacteria, archaea, viruses, and fungi, and their impact on health and the environment.
  • Molecular Biology: Zooms in on the role of molecules like DNA and RNA in cellular processes and heredity.
  • Zoology: Delves into the animal kingdom, its diversity, behavior, evolution, and conservation.
  • Botany: Focuses on plants, their structure, physiology, ecology, and evolution.
  • Ecology: Examines the interactions between living organisms and their environment, including how populations, communities, and ecosystems function.
  • Evolutionary Biology: Studies how living things change over time and the mechanisms that drive this change, such as natural selection.

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What are the Worldsupporter goals related to Biology & Biological Sciences?

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What is biology?

What is biology?

Biology is the fascinating and ever-expanding field dedicated to studying life on Earth. It encompasses all living organisms, from the microscopic world of bacteria to the towering giants of the redwood forest. Biologists delve into the structure, function, growth, origin, evolution, and distribution of life across the planet.

What are the main features of biology?

  • Diversity of Life: Biology celebrates the incredible variety of life forms, from single-celled organisms to complex ecosystems teeming with interacting species.
  • Unity in Diversity: Despite this vast diversity, there are unifying principles that tie all living things together. These include the use of DNA as genetic material and the processes of cellular respiration and photosynthesis, which power life.
  • Scientific Approach: Biologists rely on the scientific method to ask questions about living things. They gather evidence through observation and experimentation, and form testable hypotheses to understand the natural world.

What are important sub-areas in biology?

Due to the immense breadth of biology, specialization is essential. Here are some of the most prominent sub-areas:

  • Biochemistry: Focuses on the chemistry of life, exploring the structure, function, and interactions of molecules essential for biological processes.
  • Cell Biology: Explores the fundamental unit of life, the cell. It examines cell structure, function, and how different cell types work together in an organism.
  • Genetics: Investigates genes, heredity, and how traits are passed down from generation to generation.
  • Microbiology: Studies microscopic organisms like bacteria, archaea, viruses, and fungi, and their impact on health and the environment.
  • Molecular Biology: Zooms in on the role of molecules like DNA and RNA in cellular processes and heredity.
  • Zoology: Delves into the animal kingdom, its diversity, behavior, evolution, and conservation.
  • Botany: Focuses on plants, their structure, physiology, ecology, and evolution.
  • Ecology: Examines the interactions between living organisms and their environment, including how populations, communities, and ecosystems function.
  • Evolutionary Biology: Studies how living things change over time and the mechanisms that drive this change, such as natural selection.

What are key concepts in biology?

  • Cell Theory: The cornerstone of biology, stating that all living things are composed of cells, the basic units of life.
  • DNA: Deoxyribonucleic acid, the molecule that carries genetic information and is responsible for heredity.
  • Evolution by Natural Selection: The theory proposed by Charles Darwin, explaining how organisms with favorable traits are more likely to survive and reproduce, leading to evolution of populations over time.
  • Homeostasis: The ability of an organism or a biological system to maintain a stable internal environment despite external changes.
  • Metabolism: The sum of all chemical reactions that occur in living organisms, allowing them to grow, reproduce, maintain their structure, and respond to their environment.

Who are influential figures in biology?

  • Louis Pasteur: A French microbiologist whose discoveries on vaccines and fermentation had a profound impact on public health.
  • Charles Darwin: A British naturalist who revolutionized our understanding of life with his theory of evolution by natural selection.
  • Gregor Mendel: An Austrian monk considered the father of genetics for his pioneering work on inheritance
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Developmental Biology: The best concepts summarized

Developmental Biology: The best concepts summarized

Developmental Biology: The best concepts summarized

A short introduction to the best concepts of developmental biology: From a zygote to a vertebrate.

What is developmental biology?

What is developmental biology?

Developmental biology is the scientific study of how organisms grow and develop from a single cell (zygote) to their final form. It explores the underlying genetic and environmental factors that shape the development of various tissues, organs, and body structures.

What are the main features of developmental biology?

  • Interdisciplinary field: It draws on insights from genetics, molecular biology, cell biology, embryology, and evolutionary biology.
  • Focus on pattern formation: It investigates how cells organize themselves into specific patterns and structures during development.
  • Key stages of development: Developmental biologists study key stages of development, including fertilization, cleavage, gastrulation, organogenesis, and metamorphosis.

Why is developmental biology important?

  • Understanding life processes: It provides fundamental insights into the mechanisms that govern the growth and development of all living organisms.
  • Medical applications: Developmental biology has significant implications for medical research, including the study of birth defects, regenerative medicine, and cancer biology.
  • Evolutionary biology: It helps us understand the evolutionary origins of different body plans and the genetic changes that underlie them.

What are applications of developmental biology?

  • Stem cell research: Understanding developmental processes can help us harness the potential of stem cells for regenerative medicine.
  • Cancer research: Studying developmental pathways can shed light on the mechanisms that drive cancer development and progression.
  • Drug discovery: Developmental biology can be used to identify new drug targets for treating diseases related to developmental defects.
  • Agricultural biotechnology: Understanding plant development can help improve crop yields and resistance to pests and diseases.

Example

One classic example of developmental biology research is the study of Drosophila melanogaster (fruit flies). Fruit flies have been used extensively as a model organism to investigate the genetic basis of development, providing valuable insights into fundamental developmental processes.

Critical comments

  • Complexity: Developmental processes are highly complex and involve a multitude of interacting factors.
  • Ethical considerations: Research on embryonic development raises ethical concerns, particularly when involving human embryos or stem cells.
  • Species-specific differences: While many developmental principles are conserved across species, there can be significant differences in the details of development.
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What is biological ethics?

What is biological ethics?

Biological ethics is a branch of applied ethics that deals with moral issues arising from the study and application of biology. It encompasses a wide range of topics, including:

  • Genetics: Issues related to genetic testing, genetic engineering, and gene therapy
  • Medicine: Ethical considerations in medical research, patient autonomy, and end-of-life care
  • Animal welfare: Ethical treatment of animals in research, agriculture, and entertainment
  • Environmental ethics: Issues related to biodiversity conservation, climate change, and sustainable resource use

What are the main features of biological ethics?

  • Interdisciplinary nature: It draws on insights from philosophy, sociology, law, and other disciplines.
  • Complex issues: Biological ethics often involves complex moral dilemmas with no easy solutions.
  • Balancing competing interests: Biological ethics seeks to balance the interests of individuals, animals, and society as a whole.

Why is biological ethics important?

  • Guiding research and practice: Biological ethics provides a framework for making morally sound decisions in scientific research and medical practice.
  • Protecting human rights: It helps to protect the rights of individuals, such as the right to privacy and informed consent.
  • Promoting animal welfare: It ensures that animals are treated ethically in research, agriculture, and other contexts.
  • Addressing environmental concerns: It helps to address pressing environmental issues, such as climate change and biodiversity loss.

What are applications of biological ethics?

  • Informed consent: Ensuring that individuals provide informed consent for medical procedures and research participation.
  • Animal welfare guidelines: Developing and enforcing guidelines for the ethical treatment of animals in research and other settings.
  • Genetic counseling: Providing guidance to individuals and families facing genetic health issues.
  • Policy development: Developing policies related to issues such as stem cell research, gene editing, and environmental conservation.

Example

A classic example of a biological ethics dilemma is the debate over stem cell research. While embryonic stem cells offer great potential for medical advancements, their use raises ethical concerns about the destruction of human embryos. Biological ethics can help to navigate this complex issue by considering the potential benefits and harms of different approaches.

Critical comments

  • Cultural and religious differences: Biological ethics can be influenced by cultural and religious beliefs, which can make it challenging to reach universal consensus.
  • Rapid technological advancements: The rapid pace of technological advancements in biology can outpace the development of ethical guidelines, creating a need for ongoing reflection and adaptation.
  • Subjectivity: Some aspects of biological ethics involve subjective judgments about values and priorities, which can make it difficult to reach definitive conclusions.
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What is a zygote?

What is a zygote?

A zygote is the single-celled organism that forms when a sperm cell fertilizes an egg cell. It represents the initial stage of life for a new individual.  

What are the main features of a zygote?

  • Diploid: Contains a complete set of chromosomes, half from each parent.  
  • Totipotent: Has the potential to develop into any type of cell in the body.
  • Undergoes rapid division: The zygote undergoes a process called cleavage, where it rapidly divides into multiple cells.  

Why is the zygote important?

  • Genetic blueprint: It carries the genetic information that will determine the traits of the developing organism.  
  • Foundation of development: The zygote is the starting point for the entire process of embryonic development.  
  • Basis of reproduction: The formation of a zygote is essential for sexual reproduction.

What are the applications of zygote research?

  • In vitro fertilization (IVF): Zygotes are created in a laboratory setting to assist in fertility treatments.
  • Stem cell research: Zygotes can be used to derive embryonic stem cells, which have the potential to differentiate into various cell types.
  • Genetic testing: Zygotes can be tested for genetic disorders before implantation, a process known as preimplantation genetic diagnosis (PGD).  

Example

A fertilized human egg cell is a zygote. It begins its journey through the fallopian tube, eventually implanting in the uterine wall and developing into an embryo.  

Critical comments

  • Ethical concerns: The use of zygotes in research, particularly embryonic stem cell research, raises ethical questions about the beginning of life and the destruction of potential human beings.
  • Limitations: While zygotes have immense potential, their development is influenced by a complex interplay of genetic and environmental factors, making it difficult to fully understand and control.
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What is Sonic hedgehog?

What is Sonic hedgehog?

Sonic hedgehog (Shh) is a secreted signaling protein that plays a crucial role in embryonic development and tissue patterning in various organisms. It is a member of the Hedgehog family of proteins, which are highly conserved across different species.

What are the main features of Sonic hedgehog?

  • Morphogen: Shh acts as a morphogen, meaning it can influence the development of different cell types and tissues based on its concentration gradient.
  • Patterning: Shh is involved in the patterning of various structures, including the nervous system, limbs, and facial features.
  • Regulation: The activity of Shh is tightly regulated by a complex network of signaling pathways and feedback mechanisms.

What is the importance of Sonic hedgehog?

Shh is essential for proper embryonic development and the formation of various organs and tissues. Dysregulation of Shh signaling can lead to birth defects and developmental disorders.

What are the applications of Sonic hedgehog in practice?

Understanding Shh signaling has significant implications for medicine and research. Some applications include:

  • Stem cell research: Shh can be used to induce the differentiation of stem cells into various cell types, such as neurons and muscle cells.
  • Cancer research: Shh signaling is implicated in the development and progression of certain types of cancer, and targeting Shh pathways may be a potential therapeutic strategy.
  • Developmental biology: Studying Shh signaling can help researchers understand the mechanisms that underlie the formation of complex structures and patterns during embryonic development.

Example

A well-known example of Shh signaling is its role in limb development. Shh is produced in the zone of polarizing activity (ZPA) at the posterior end of the limb bud. The concentration gradient of Shh across the limb bud helps to determine the patterning of digits, with the thumb being formed by cells exposed to the highest concentration of Shh and the pinky finger being formed by cells exposed to the lowest concentration.

Critical comments

While Shh is a well-studied signaling molecule, there are still many unanswered questions about its precise mechanisms of action and regulation. Further research is needed to fully understand the complex interactions between Shh and other signaling pathways that contribute to embryonic development and tissue patterning.

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Latest blogs, jobs, projects, organizations, and tips tagged with: Biology & Biological Sciences

Iracambi

Deze lokale organisatie biedt vrijwilligerswerk en stages aan op het gebied van natuurbehoud en wetenschappelijk onderzoek in Brazilië. Zo kun je bijvoorbeeld meewerken op het landgoed van de duurzame koffieplantages en zo meer leren over het planten en oogsten van koffie. Een andere mogelijkheid is het in kaart brengen van veranderingen in de bossen, door middel van het nemen van onder andere bodem monsters. Ook het bijhouden van de website of het doen aan fondsenwerving behoren tot de mogelijkheden. Het Atlantic forest van Brazilië heeft veel last van ontbossing. Bomen planten en het watersysteem herstellen is een van de

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Coral Cay Conservation

Deze Engelse Marine Wildlife onderzoeksorganisatie treed ook op als bemiddelingsorganisatie voor vrijwilligerswerk gericht op het behoud van de onderwaterwereld in Sinai, Egypte. Zo kun je bijvoorbeeld meehelpen aan het behoud van koraalriffen door middel van onderzoek en het afbakenen van duikgebieden. Of werk je mee aan het geven van voorlichting over het belang van het behoud van de onderwaterwereld op verschillende scholen. Tot 2021 was deze organisatie met name actief op de Filipijnen, maar hebben alle activiteiten overgezet naar Egypte.

Diverse stage mogelijkheden binnen marketing en het organiseren van events. Voor mogelijkheden neem contact op met de organisatie.

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What is the Spemann organizer?

The Spemann organizer, also known as the dorsal blastopore lip, is a small region of tissue in the amphibian embryo that plays a crucial role in determining the body plan. It is named after Hans Spemann, a German embryologist who discovered its importance in the early 20th century.

What are the main features of the Spemann organizer?

  • Dorsal location: It is located on the dorsal side of the blastopore, the opening that forms during gastrulation.
  • Inductive properties: It has the ability to induce the formation of the dorsal axis of the embryo, including the nervous system and notochord.
  • Organizer of polarity: It establishes the anterior-posterior and dorsal-ventral axes of the embryo.

Why is the Spemann organizer important?

  • Body plan determination: It is a key determinant of the body plan, influencing the development of the head, trunk, and tail.
  • Neural induction: It plays a crucial role in
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What is ingression?

Ingression is a process in embryonic development where individual cells migrate from the surface layer (ectoderm or mesoderm) into the interior of the embryo. It is a fundamental mechanism that contributes to the formation of various tissues and organs.

What are the main features of ingression?

  • Individual cell migration: Cells migrate independently, rather than as a sheet.
  • Cellular differentiation: Ingressing cells often undergo differentiation to become specialized cell types.
  • Tissue formation: Ingression plays a crucial role in the formation of tissues and organs, such as the mesoderm and nervous system.

Why is ingression important?

  • Germ layer formation: Ingression is involved in the formation of the mesoderm, one of the three primary germ layers.
  • Body axis establishment: It contributes to the establishment of the anterior-posterior and dorsal-ventral axes of the embryo.
  • Morphogenesis: Ingression is a fundamental process in morphogenesis, the shaping and patterning of the developing embryo.
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What is invagination?

Invagination is a biological process where a sheet of cells folds inward to form a pocket or tube. It is a common mechanism in embryonic development and plays a crucial role in the formation of various structures.

What are the main features of invagination?

  • Cell movement: Invagination involves the coordinated movement of cells.
  • Shape change: The shape of the tissue undergoes a dramatic transformation.
  • Formation of internal structures: Invagination is often used to create internal structures, such as the digestive tract and nervous system.

Why is invagination important?

  • Germ layer formation: Invagination is essential for the formation of the endoderm, one of the three primary germ layers.
  • Body axis establishment: It contributes to the establishment of the anterior-posterior and dorsal-ventral axes of the embryo.
  • Morphogenesis: Invagination is a fundamental process in morphogenesis, the shaping and patterning of the developing embryo.

What are applications of invagination

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What is epiboly?

Epiboly is a process in embryonic development where a sheet of cells spreads over the surface of another cell mass. It is a fundamental mechanism that contributes to the formation of various structures in the embryo.

What are the main features of epiboly?

  • Cell spreading: Cells migrate outward and expand, covering a larger area.
  • Shape change: The shape of the cell sheet often changes during epiboly.
  • Tissue formation: Epiboly plays a crucial role in the formation of tissues and organs, such as the skin and nervous system.

Why is epiboly important?

  • Germ layer formation: Epiboly is involved in the formation of the ectoderm and mesoderm, two of the three primary germ layers.
  • Body axis establishment: It contributes to the establishment of the anterior-posterior and dorsal-ventral axes of the embryo.
  • Morphogenesis: Epiboly is a fundamental process in morphogenesis, the shaping and patterning of the developing embryo.
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What is gastrulation?

Gastrulation is a crucial stage in embryonic development during which the blastula (a hollow ball of cells) reorganizes to form the three primary germ layers: the ectoderm, mesoderm, and endoderm. These germ layers will ultimately differentiate into all the tissues and organs of the developing embryo.

What are the main features of gastrulation?

  • Formation of germ layers: The process involves the inward movement of cells, creating three distinct layers.
  • Establishment of body axes: Gastrulation also establishes the anterior-posterior (head-tail) and dorsal-ventral (back-belly) axes of the embryo.
  • Morphogenesis: It is a critical step in morphogenesis, the process of shaping and patterning the developing embryo.

Why is gastrulation important?

  • Germ layer formation: The three germ layers formed during gastrulation give rise to all the tissues and organs of the body.
  • Body axis establishment: The establishment of the body axes is essential for proper development and function of the
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What is developmental biology?

Developmental biology is the scientific study of how organisms grow and develop from a single cell (zygote) to their final form. It explores the underlying genetic and environmental factors that shape the development of various tissues, organs, and body structures.

What are the main features of developmental biology?

  • Interdisciplinary field: It draws on insights from genetics, molecular biology, cell biology, embryology, and evolutionary biology.
  • Focus on pattern formation: It investigates how cells organize themselves into specific patterns and structures during development.
  • Key stages of development: Developmental biologists study key stages of development, including fertilization, cleavage, gastrulation, organogenesis, and metamorphosis.

Why is developmental biology important?

  • Understanding life processes: It provides fundamental insights into the mechanisms that govern the growth and development of all living organisms.
  • Medical applications: Developmental biology has significant implications for medical research, including the study of birth defects, regenerative medicine, and cancer biology.
  • Evolutionary
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What is biological ethics?

Biological ethics is a branch of applied ethics that deals with moral issues arising from the study and application of biology. It encompasses a wide range of topics, including:

  • Genetics: Issues related to genetic testing, genetic engineering, and gene therapy
  • Medicine: Ethical considerations in medical research, patient autonomy, and end-of-life care
  • Animal welfare: Ethical treatment of animals in research, agriculture, and entertainment
  • Environmental ethics: Issues related to biodiversity conservation, climate change, and sustainable resource use

What are the main features of biological ethics?

  • Interdisciplinary nature: It draws on insights from philosophy, sociology, law, and other disciplines.
  • Complex issues: Biological ethics often involves complex moral dilemmas with no easy solutions.
  • Balancing competing interests: Biological ethics seeks to balance the interests of individuals, animals, and society as a whole.

Why is biological ethics important?

  • Guiding research and practice: Biological ethics provides a framework for making morally
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What are somites?

Somites are blocks of mesoderm that form on either side of the notochord during embryonic development in vertebrates. They play a crucial role in the formation of various tissues and organs throughout the body.

What are the main features of somites?

  • Mesodermal origin: They are derived from the paraxial mesoderm.
  • Segmental arrangement: They are arranged in a segmental pattern along the length of the embryo.
  • Differentiation into various tissues: Somites differentiate into a variety of tissues, including:
    • Skeletal muscle
    • Cartilage
    • Bone
    • Dermis (the deeper layer of skin)
    • Tendons
    • Fascia

Why are somites important?

  • Body segmentation: They establish the basic body plan of vertebrates, including the segmentation of the spine and ribs.
  • Tissue differentiation: They provide the cellular building blocks for a wide range of tissues and organs.
  • Muscle development: They are the primary source of skeletal muscle, which is essential for movement and
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What is carrying capacity?

The carrying capacity of an ecosystem is the maximum population size of a species that the ecosystem can sustain indefinitely, given the food, water, and other resources available. What are the key characteristics of carrying capacity?

  • Dynamic: Carrying capacity is not a fixed number, ...

What is transcriptomics?

Transcriptomics is the field of science devoted to studying the transcriptome. The transcriptome is the entire collection of RNA molecules within a cell, tissue, or organism at a specific point in time. It essentially represents a snapshot of the genes that are currently being expressed, offering a ...

What is proteomics?

Proteomics is the science dedicated to comprehensively studying proteomes. A proteome refers to the entire set of proteins produced by an organism, system, or even a specific cell at a particular time. Unlike genes in genomics, which remain relatively constant, the proteome is dynamic and reflects t...

What is metabolomics?

Metabolomics delves into the fascinating world of metabolites. These are the small molecule substrates, intermediates, and products of cellular metabolism, the intricate network of chemical reactions keeping organisms alive. By studying the metabolome, the complete collection of metabolites within a...

What is a plasmid?

Plasmids are fascinating extrachromosomal DNA molecules found in bacteria, and sometimes in archaea and eukaryotes. Unlike chromosomal DNA, which holds the essential blueprint for an organism, plasmids are independent genetic elements that can replicate on their own. What are the key features of pla...

What is Polymerase Chain Reaction?

PCR, which stands for Polymerase Chain Reaction, is a revolutionary technique used to amplify specific DNA sequences. It allows researchers to rapidly generate millions of copies of a targeted DNA segment from a very small sample. What are the key features of PCR?

  • Specificity: PCR relies on...

What is Next Generation Sequencing?

Next-generation sequencing (NGS), also known as massively parallel sequencing, is a powerful technology that has revolutionized the field of genomics. Unlike traditional Sanger sequencing, which analyzes one DNA molecule at a time, NGS allows researchers to sequence millions or even billions of DNA ...

What is Sanger sequencing?

Sanger sequencing, also known as the dideoxy chain termination method, is a pioneering technique for determining the order of nucleotides (A, C, G, T) in a DNA molecule. Developed by Frederick Sanger and his colleagues in 1977, it paved the way for modern DNA sequencing methods. What are the key fea...

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What is biological sciences?

Biological sciences, also commonly referred to as biology, is the overarching field dedicated to studying life on Earth in all its forms. It encompasses a vast array of disciplines, each focusing on different aspects of living organisms. What are the main features of biological sciences?

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Summary: Essential Cell Biology (Alberts et al) - Second part

This summary is based on the 3rd edition of Essential Cell Biology from Alberts et al. The first 10 chapters are open access and can be found here: First part of the summary

  • 11. Membrane structure
  • 12. Membrane transport
  • 13. How cells obtain energy from food
  • 14. E...

What is biological sciences?

Biological sciences, also commonly referred to as biology, is the overarching field dedicated to studying life on Earth in all its forms. It encompasses a vast array of disciplines, each focusing on different aspects of living organisms. What are the main features of biological sciences?

    <...>

Summary: Essential Cell Biology (Alberts et al) - First part

This summary is based on the 3rd edition of Essential Cell Biology from Alberts et al. The remaining chapters can be accessed when logged in and can be found here: Second part of the summary

  • 1. Introduction to cells
  • 2. Chemical components of cells
  • 3. Energy, cat...

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