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RNA-sequencing (RNA-seq) is a powerful technique that allows researchers to comprehensively analyze the transcriptome. The transcriptome refers to the entire collection of RNA molecules (messenger RNA, ribosomal RNA, transfer RNA, and other non-coding RNAs) present within a cell, tissue, or organism at a specific point in time. By studying the transcriptome, RNA-seq offers a dynamic snapshot of gene expression, revealing which genes are actively being transcribed into RNA and at what level.
Researchers are studying a new drug for Alzheimer's disease. They can use RNA-seq to compare gene expression profiles in healthy brain cells versus those affected by Alzheimer's. This can reveal changes in genes associated with memory, inflammation, or other processes relevant to the disease. By analyzing how the drug affects these gene expression patterns, they can assess its potential therapeutic benefits.
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