Summary with the article: Epigenetics: Stress makes its molecular mark - Nestler (2012)

Some people who are exposed to stress are more vulnerable to negative outcomes than others. Differences in epigenetics may explain this vulnerability. Epigenetic mechanisms provide short and long-term responses to stress.

Aggressive mice

When a person is stressed, gene expressions in areas the brain will be activated or inhibited. Many stress-induced changes are adaptive, but some are also harmful and can be permanent. Research has been done using mice which were exposed to other, aggressive mice. After ten days of this experiment, the mice started to avoid these other mice. They also became less interested, less adventurous and more likely to be obese. These symptoms could last for months and could be treated with antidepressants. It turned out that mice that had been given cocaine a week before being exposed to aggressive mice had more stress-related

H1: Introductie tot de Psychoneuroimmunologie

Hieronder worden het doel en de belangrijkste thema’s van de samenvatting beschreven.
 

Het doel

De term psychoneuroimmunologie stamt uit het jaar 1980 en werd destijds geïntroduceerd door Robert Ader. Hij benadrukte hiermee de fundamentele eenheid van het lichaam om de gezondheid te handhaven. Het doel van het boek