Addiction and compulsions
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Brain dopamine and obesity
Wang, Volkow, Logan, Pappas, Wong, Zhu & Fowler (2001)
The Lancet
The availability of dopamine D2 receptor was decreased in obese individuals in proportion to their MBI. Dopamine modulates motivation and reward circuits and hence dopamine deficiency in obese individuals my perpetuate pathological eating as a means of compensate for decreased activation of these circuits.
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