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Blok AWV HC1: Research questions
HC1: Research questions
Medical research
The ultimate goal of medical research is to improve medical practice. There are different aspects of medical practice which form 4 classes of medical research:
- Etiology (prevention/risk factors of a medical disease)
- Is a high caloric diet a risk factor for cardiovascular disease?
- Diagnosis
- What is the probability of having a hip fracture if the affected leg is shorter and in exorotation?
- Treatment
- Does chloroquine treatment reduce the risk of mortality among COVID-19 patients admitted to the ICU?
- Prognosis
- What is the probability of dying within 5 years after breast cancer diagnosis?
Research questions
Research questions arise in practice. It is important to particularly articulate a research question → they are the starting point when designing a study or when reading a paper. A research question should be answerable and have standard elements/components.
Components:
Research questions can consist of several types of standard components:
- PICO: most often used
- Patient (population)
- Intervention
- Comparator
- Outcome
- DDO
- Domain
- Determinant
- Outcome
Examples:
Examples of research questions are:
- To what extent does alemtuzumab compared to interferon-β improve the time until relapse occurs in patients with relapsing remitting MS?
- Classification: treatment
- Patients: patients with relapsing remitting MS
- Intervention: alemtuzumab
- Comparator: interferon-β
- Outcome: time until relapse occurs
- What is the predictive value of a second ultrasound, in case a first ultrasound was inconclusive, in patients suspected of having an acute appendicitis?
- Classification: diagnosis
- Patients: patients suspected of having an acute appendicitis, in whom a first ultrasound was inconclusive
- Intervention: second ultrasound
- Comparator: /
- Outcome: appendicitis
- Is smoking a risk factor for lung cancer?
- Classification: etiology
- Patients: humans
- Intervention: smoking
- Comparator: no smoking
- Outcome: lung cancer
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This content is used in:
Blok AWV2 2020/2021 UL
- Blok AWV HC1: Research questions
- Blok AWV HC2: RCT
- Blok AWV HC3: Sample size calculation
- Blok AWV HC4: Cohort studies
- Blok AWV HC5: Case control studies
- Blok AWV HC6+7: Bias
- Blok AWV HC8+9: Survival analysis
- Blok AWV HC10+11: Regression analysis
- Blok AWV HC12: Diagnostische begrippen
- Blok AWV HC13: Beslisbomen
- Blok AWV HC14: Test en behandeldrempel
This content is also used in .....
Blok AWV2 2020/2021 UL
Deze bundel bevat alle aantekeningen van de colleges uit het blok AWV uit het 2e jaar van de bachelor Geneeskunde aan de Universiteit Leiden. Ook aantekeningen uit de werkgroepen zijn in de samenvattingen verwerkt.
- Read more about Blok AWV2 2020/2021 UL
- 1557 reads
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