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Article summary of Childhood maltreatment predicts an unfavorable course of illness and treatment outcome in depression: a meta-analysis by Nanni et al. - Chapter

Preface

Social relevance

Depressions have major consequences for health and cause a high economic burden for society. Because of this, it is important to study the risks of developing recurrent and severe depression and inadequate responding to treatment.

The role of child abuse

Child abuse predicts an unfavorable course of depression and leads to unfavorable treatment outcomes. People who have experienced child abuse have a high risk on developing depression.

Meta-analysis

This article describes a meta-analysis that examines the relationship between child abuse and an increased risk of depression and negative treatment outcomes. For people with depression and a history of child abuse, it was checked whether there were recurrent depressive periods and persistent depressive symptoms. The relationship between child abuse and various treatments was also examined. The types of treatment considered are psychological and pharmacological (medication) treatments and a combination of the two.

Method

Literature has been used that describes the relationship between child abuse and disease progression (such as recurrence and persistence) and treatment outcomes in depression. Recurrence was defined in terms of the number of depressive periods. Persistence was defined as the duration of the current depression. Treatment outcome was defined in terms of treatment response and remission (reduction or disappearance of symptoms of depression).

Results

Epidemiological studies

A meta-analysis among these studies showed that people with a history of child abuse were twice as likely to have an unfavorable course of depression than people without a history of child abuse.

Recurrence and severity of depression

The results showed that people with a history of child abuse suffered twice as often from recurrent depressive periods compared to people without a history of child abuse. The severity and persistence of depressive symptoms was also investigated in the group with a history of child abuse. This group also appeared to suffer twice as often from more severe and persistent depression periods.

Treatment outcomes: psychotherapy, pharmacology, combination therapy

The results of the meta-analysis showed that people with a history of child abuse were more likely to respond poorly to treatment compared to people without a history of child abuse. In psychotherapy, people who had been abused, did not significantly respond poorly to treatments. For pharmacology, a significantly higher risk was found for poor treatment outcomes in people with a history of child abuse. The group of abused persons also appeared to achieve a worse treatment result when in combined (psychological and pharmacological) treatment.

Discussion

This meta-analysis showed that people with a history of child abuse had recurrent and persistent depressive symptoms twice as often as people without a history of child abuse. This group of abused persons also appeared to benefit less from treatments. This in turn is a risk factor for recurrent and persistent depressive periods. In the context of depression, early prevention of child abuse is important for improving health and reducing the economic burden.

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Summaries per article with of Psychological and Neurobiological Consequences of Child Abuse at Leiden University 21/22

Summaries per article with of Psychological and Neurobiological Consequences of Child Abuse at Leiden University 21/22

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Kindermishandeling & Jeugdzorg: samenvattingen van de beste wetenschappelijke artikelen

Of je nu meer wil weten over de forensisch-medische aspecten van kindermishandeling, of benieuwd bent naar hoe desinformatie in het geheugen geplant kan worden - bij de top 40 van samenvattingen van de wetenschappelijke artikelen over kindermishandeling wordt kindermishandeling en jeugdzorg vanuit een breed spectrum bestudeerd en behandeld.

Kindermishandeling & Jeugdzorg: een selectie van ongeveer 40 samenvattingen van de beste wetenschappelijke artikelen (alfabetische volgorde), gebaseerd op diverse vakken rond dit thema zoals aangeboden aan de Universiteiten van Leiden, Utrecht en Groningen voor de studies Pedagogiek en Psychologie.

De opgesomde titels zijn in de meeste gevallen vrije vertalingen van de originele Engelstalige titels:

  • Begrijpen van de adolescentie als een periode van sociale en affectieve betrokkenheid en flexibiliteit wat betreft doelen - Crone, Dahl
  • Behandeling voor chronische depressie met een schema therapie - Renner et al
  • Bijwerkingen van jeugdervaringen in het leven van vrouwelijke zedendelinquenten - Levenson
  • Consequenties van kindermishandeling in landen met hoge inkomens - Gilbert et al
  • De cumulatieve effecten van de risico- en beschermende factoren van moeders op storend gedrag van hun dochters - van der Molen et al
  • De ontwikkeling van de communicatieve en narratieve vaardigheden bij peuters en kleuters: lessen van forensische interviews over kindermishandeling - Hershkowitz
  • DNA-methylatie, Gedrag en tegenspoed in Early Life - Szyf
  • Einstein op de bank? Gebrek aan wetenschappelijk bewijs om rechtszaken van kindermishandeling te kunnen beoordelen - Moreno
  • Emotiemodulatie bij PTSD: klinisch en neurobiologisch bewijs voor een dissociatief subtype - Lanius et al
  • Forensisch-medische aspecten van kindermishandeling - Kemp
  • Genetische gevoeligheid voor het milieu - Caspi et al
  • Geriatrische forensische evaluees: een studie - Lewis et al
  • Gezondheidseffecten van kindermishandeling - Kendall-Tackett
  • Het geheugen van kinderen als ooggetuigen: de invloed van cognitieve en sociaal-emotionele factoren - Goodman et al
  • Het probleem met kinderartsen - Williams
  • Het seksueel welzijn van vrouwen die seksueel misbruik hebben ervaren - Lemieux et al
  • Jeugd stress heeft aanhoudende effecten op het functioneren van de amygdala en de ontwikkeling van muizen en mensen - Cohen et al
  • Jeugdige en volwassen zedendelinquenten - Hendriks, Bijleveld
  • Kindermishandeling en DSM-VI mentale stoornissen van volwassenen - Scott et al
  • Kindermishandeling voorspelt een ongunstig depressiebeloop en ongunstige behandeluitkomsten bij depressieve mensen: een meta-analyse - Nanni et al
  • Meta-analyse van psychologische behandelingen voor PTSS bij volwassenslachtoffers van kindermishandeling - Ehring et al
  • Neurobiologische en psychiatrische consequenties van kindermishandeling en verwaarlozing - Heim et al
  • Neurologische kijk op kindermishandeling: een kritische review - Hart, Rubia
  • Onthullingen van seksueel misbruik van kinderen - London et al
  • Onvoorspelbaarheid van vroege ervaringen op mentale stoornissen - Baram et al
  • Openbaarmaking van seksueel misbruik bij kinderen: een model - Goodman-Brown et al
  • Overtreding onder ouderen - Curtice et al
  • Scheidingservaringen in de kindertijd voorspellen hormonale respons van de HPA as in late volwassenheid - Pesonen et al
  • Seksueel misbruik bij kinderen en zwangerschap tijdens de adolescentie - Noll et al
  • Seksueel misbruik bij kinderen, een case study - Leander et al
  • Seksuele problemen en PTSS na seksueel trauma: Een meta-analyse - O'Driscoll et al
  • Telomeren en tegenspoed:
.......read more
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