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Next-generation sequencing (NGS), also known as massively parallel sequencing, is a powerful technology that has revolutionized the field of genomics. Unlike traditional Sanger sequencing, which analyzes one DNA molecule at a time, NGS allows researchers to sequence millions or even billions of DNA fragments simultaneously.
A researcher suspects a genetic component might be contributing to a specific eye disease. They can use NGS to sequence the entire genomes of patients with the disease and healthy controls. By comparing the sequences, they can identify genetic variations potentially associated with the disease, leading to the development of diagnostic tests or targeted therapies.
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